- Prevention of clotting in arterial and heart surgery
- Disseminated Intravascular Coagulation (DIC)
- Atrial fibrillation with embolization
- DVT and Pulmonary embolism
- Hematology: Thrombocytopenia, bleeding, bruising, injection-site reactions,
- Skin: hair loss,
- GI: liver enzyme changes
- Heparin is a High Alert Medication
- Adjust dose based on lab results.
- Dosage is considered adequate when the activated partial thromboplastin time (APTT) is 1.5 to 2 times normal
- Give by deep subcutaneous injections; do not give IM.
- Have protamine sulfate on hand as antidote.
- Protect clients from injury, report bleeding gums, black or tarry stools, and severe headache.
- Avoid intramuscular route of administration because of the frequent occurrence of hematoma at the injection site.
- Always follow facility’s heparin protocol, whenever working with this medication.
Ref: Roach’s Introductory Clinical Pharmacology
To Your Success!