Sinemet is used to treat Parkinson’s disease.

• Classifications: Autonomic Nervous System Agent; Anticholinergic; Antiparkinsonism Agent
• Available in Capsule & Tablet forms

Geriatric

• Elderly patients may have increase chance of side effects during treatment due to high sensitivity.

Contraindications

• Narrow-angle glaucoma
• Pregnancy (category C)

Caution in

• Kidney disease
• Diabetes mellitus
• Chronic lung disease

Side effects

• Urine, saliva, and sweat become darker in color than usual.
• May cause a bitter taste, or a burning sensation of the tongue

Interactions – MAOI, Tricyclic antidepressants, Haloperidol

Nursing Implications

• Observe for therapeutic effects and report adverse reactions promptly.
• Monitor vital signs & rhythm, particularly during period of dosage adjustment.

Patient teaching

• Teach to make position changes slowly, particularly from sitting to upright position.

Reference: Roach’s Introductory Clinical Pharmacology. 

To Your Success!

Rophem 🙂