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Tag Archives: Antiepileptic

NCLEX Pharm: Dilantin

Generic name: Phenytoin Sodium. Brand name: Dilantin

Class: Antiepileptic, Anticonvulsant, Antiarrhythmic

Indication: Seizures, Cardiac Arrhythmias

Side effects:

  • Hematology: aplastic anemia, hematopoietic complications,
  • Neuro: ataxia, dizziness, drowsiness, insomnia
  • Skin: purpuric dermatitis, Steven-Johnson syndrome.
  • GI: gingival hyperplasia, liver damage

Nursing Tips:

  • Therapeutic serum level 10-20 mcg/ml
  • Do not stop abruptly, to prevent status epilepticus.
  • Stop if rash, depressed blood count, enlarged lymph nodes, hypersensitivity reaction, signs of liver damage develop.
  • Not for use in pregnancy, it will cause fetal hydantoin syndrome; mental & physical birth defects.
  • Phenytoin is occasionally used in the treatment of cardiac arrhythmias, those associated with digitalis intoxication
  • Continually monitor cardiac rhythm; check BP frequently.
  • Dilantin capsules should be taken by mouth, swallowed whole. Do not open or crush medication.
  • Patient should take medication with a full glass (8 ounces) of water unless the doctor directs otherwise.
  • Dilantin should be used regularly and all doses taken on time to keep the serum level constant.
  • Products that contain calcium (e.g., antacids, calcium supplements) and nutritional tube-feeding products may decrease the absorption of phenytoin. Separate liquid nutritional products at least 1 hour before and 1 hour after phenytoin dose.

To your Success!

Rophem 🙂

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